Galleria mellonella experimental model: advances and future directions
نویسندگان
چکیده
منابع مشابه
New to Galleria mellonella
EditoriAL Pathogens and their respective hosts interact closely leading to the host–pathogen framework response that could result in different outcomes that range from pathogen elimination to death of the host. To improve our ability to propose new measures that promote pathogen elimination and prevent host death, we need to have a comprehensive understanding of this interaction. Generally , mo...
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Legionella pneumophila is a facultative intracellular human pathogen and the etiological agent of severe pneumonia known as Legionnaires' disease. Its virulence depends on protein secretion systems, in particular, the Dot/Icm type IV secretion system (T4SS), which is essential to establish a replication-permissive vacuole in macrophages. The analysis of the role of these systems and their subst...
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The number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be establi...
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ژورنال
عنوان ژورنال: Pathogens and Disease
سال: 2021
ISSN: 2049-632X
DOI: 10.1093/femspd/ftab021